What is YL9900 MS?

YL9900 MS quickly provides essential information and improves the chemist’s workflow.

Mordern organic labs have become automated, yet real-time mass assays remain just out of reach.
YL9900 MS solves this !

YL 9900 MS is the smartest instrument for performing a mass spec  solution, if you are a bio pharmaceutical company, academic teaching/research lab or any industry requiring mass assays.

YL9900 MS Delivers

  • Positive and negative ions analysis
  • ESI / APCI (switchable with minimal effort, optional installation)
  • The first mass spec which fits in a fume hood with the sash closed
  • Easy access to the YL9900 MS :
    10 connectors located on the front of the instrument
    (8 I/O connectors, USB port and computer connector)
  • Integrated solutions :
    – FIA
    – LC or UPLC
    – Flash
    – Reaction monitoring
    – TLC


  • An inviting interface with powerful depth
    – Mass ExpressTM, Data ExpressTM.
  • YL-Clarity both LC and MS with MS Extension only.

Maximize your Results and Investment

Elegant stand – alone Integrated solution

Flow Injection Analysis

(Direct Injection)

Real-time reaction monitoring :
Understand kinetics and reach intelligent quench


A mass detector which can be integrated into
existing HPLC and UPLC systems
Replacing expensive mass spectrometers
purchased from another era

Flow Synthesis / MS

On-line flow chemistry reaction monitoring

Flash / MS

Mass directed (or Mass confirmed, UV directed)
fraction collection from normal phase flash
chromatography, prep LC and SFC.


Mass confirmation of flash fraction :
Eliminate TLC plate spotting or 2nd guessing UV
peaks and TLC spots

Mass Express™ for the MS control
Data Express™ for the Data processing


We focused in the minimum steps and most efficient range of motion required for decision-bearing answer.

Ultimate confidence!

You can export cdf and csv files and you have thought of all possible options  for data archiving and interpretation.

Auto tune

The YL9900 MS uses a pressurize calibrant delivery system for both
positive and negative tuning mixes which are placed inside.

You can also set parameters manually.


You can overcome poor resolution with UV detector or other detectors.
Selective ion mode gives you a high selectivity for all individual chemicals.


Whether your application is FIA, Flash, LC, UPLC or flow reaction monitoring, our data acquisition and workflow approaches are the same.

The smartest mass spec designed just for Chemists!


Mass Analyzer: Single Quadrupole
Mass Range: 10 – 1,200 m/z
Scan Speed: 5,000 m/z/s
Ion Source: ESI / APCI (Option)
Polarity: Positive / Negative
HPLC Flow Rate: 10 – 500 μL/min
Resolution: 0.5 – 0.7 m/s (FWHM) at 1,000 m/z/s
Sensitivity: 10 pg reserpine (FIA – 5 μL injection at 100 μL/min)
100:1 S/N (RMS) with SIM of m/z 609.28
100 pg reserpine (FIA – 5 μL injection at 100 μL/min)
100:1 S/N (RMS) with full-scan acquisition from m/z 100 to m/z 1,200

Accuracy: ± 0.1 m/z
Stability: 0.1 m/z over 12 hour
Gas: N2, 98 %, 60 psi
Gas Consumption: 8 L/min
Weight: 32 kg
Dimensions: (H × W × D, mm) 660 × 280 × 560
Power Consumption: Max. 300 VA (MS)
Max. 550 VA (Rotary pump)
Software: Mass ExpressTM / Data ExpressTM
Warranty: 1 year

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